The Anti-PAPLN Mouse mAb Antibody from MyBioSource.com is a Mouse Monoclonal antibody to PAPLN. This antibody recognizes Human, and Mouse antigen. The Anti-PAPLN Mouse mAb Antibody has been validated for the following applications: Immunocytochemistry, and Western Blot.
Description
Entrez Summary: Papilin is an extracellular matrix glycoprotein involved in, thin matrix layers during gastrulation, matrix associated with wandering, phagocytic hemocytes, basement membranes and space-filling matrix during Drosophila development.Determination of its cDNA sequence led to the identification of Caenorhabditis and mammalian papilins. A distinctly conserved 'papilin cassette' of domains at the amino-end of papilins is also the carboxyl-end of the ADAMTS subgroup of secreted, matrix-associated metalloproteinases; this cassette contains one thrombospondin type 1 (TSR) domain, a specific cysteine-rich domain and several partial TSR domains. In vitro, papilin non-competitively inhibits procollagen N-proteinase, an ADAMTS metalloproteinase